I cried the first time I held a Nintendo 3DS. The experience was a revelation that I'll not soon forget, and even if everyone stopped making games for it tomorrow, my blue 3DS XL is not going anywhere. That little machine is a window into a part of human experience that most people take for granted, but which is otherwise inaccessible to me.
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Public release date: 29-Apr-2013
Share ] Contact: Rachel Steigerwald
media@gastro.org
301-272-1603
American Gastroenterological Association
Bethesda, MD (April 29, 2013) A commonly used class of biologic response modifying drugs can cause acute liver injury with elevated liver enzymes, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. Patients with inflammatory diseases such as Chron's disease or ulcerative colitis often are prescribed tumor necrosis factor-alpha (TNF-?) antagonists, which modify the body's response to infection. Patients with inflammatory arthropathies and selected dermatological diseases are also candidates to receive such compounds.
"TNF-? antagonists are extremely beneficial as therapies for several bowel, joint and skin inflammatory conditions," said Maurizio Bonacini, MD, AGAF, study author and associate clinical professor, University of California, San Francisco. "However, gastroenterologists, internists, rheumatologists and dermatologists all need to be aware of this potential complication and know how to diagnose it. They should conduct tests for autoimmunity early upon diagnosis of abnormalities to determine the proper path of care."
Researchers searched the U.S. Drug-Induced Liver Injury Network database and identified six well-characterized cases of drug-induced liver injury (DILI) in the setting of TNF-? antagonist therapy. Additionally, they reviewed 28 additional cases identified in PubMed. The researchers found acute liver injury in all cases, most frequently autoimmunity and hepatocellular injury, but mixed non-autoimmune patterns and cholestasis (blocked flow of bile from the liver) also occurred. No deaths were attributed to the liver injury; one patient required a liver transplant, which was attributed to pre-existing cirrhosis with superimposed DILI.
Of the TNF-? antagonists, infliximab-associated liver injury has been the best documented, most likely because of its earlier approval and more wide-spread clinical use. Etanercept and adalimumab have also been linked to drug-induced liver injury. So far, there are no published cases found to be linked to natalizumab, golimumab or certolizumab.
The researchers found that liver damage was typically resolved following drug discontinuation, although some patients did benefit from a course of corticosteroids. Importantly, patients treated with an alternative TNF-? after resolution of their liver injury appeared to tolerate the drugs without recurrence.
"If patients who are taking these biologic agents experience symptoms such as abdominal pain, nausea and fatigue, physicians should check liver enzyme levels to determine if the symptoms are a result of these drugs," added Dr. Bonacini.
###
About the AGA Institute
The American Gastroenterological Association is the trusted voice of the GI community. Founded in 1897, the AGA has grown to include 17,000 members from around the globe who are involved in all aspects of the science, practice and advancement of gastroenterology. The AGA Institute administers the practice, research and educational programs of the organization. http://www.gastro.org.
About Clinical Gastroenterology and Hepatology
The mission of Clinical Gastroenterology and Hepatology is to provide readers with a broad spectrum of themes in clinical gastroenterology and hepatology. This monthly peer-reviewed journal includes original articles as well as scholarly reviews, with the goal that all articles published will be immediately relevant to the practice of gastroenterology and hepatology. For more information, visit http://www.cghjournal.org.
Like AGA (https://www.facebook.com/AmerGastroAssn) and Clinical Gastroenterology and Hepatology (http://www.facebook.com/cghjournal) on Facebook.
Join AGA on LinkedIn (http://www.linkedin.com/groups?mostPopular=&gid=915257).
Follow us on Twitter @AmerGastroAssn (http://www.twitter.com/amergastroassn).
Check out our videos on YouTube (http://www.youtube.com/amergastroassn).
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 29-Apr-2013 Share ] Contact: Rachel Steigerwald
media@gastro.org
301-272-1603
American Gastroenterological Association
Bethesda, MD (April 29, 2013) A commonly used class of biologic response modifying drugs can cause acute liver injury with elevated liver enzymes, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association. Patients with inflammatory diseases such as Chron's disease or ulcerative colitis often are prescribed tumor necrosis factor-alpha (TNF-?) antagonists, which modify the body's response to infection. Patients with inflammatory arthropathies and selected dermatological diseases are also candidates to receive such compounds.
"TNF-? antagonists are extremely beneficial as therapies for several bowel, joint and skin inflammatory conditions," said Maurizio Bonacini, MD, AGAF, study author and associate clinical professor, University of California, San Francisco. "However, gastroenterologists, internists, rheumatologists and dermatologists all need to be aware of this potential complication and know how to diagnose it. They should conduct tests for autoimmunity early upon diagnosis of abnormalities to determine the proper path of care."
Researchers searched the U.S. Drug-Induced Liver Injury Network database and identified six well-characterized cases of drug-induced liver injury (DILI) in the setting of TNF-? antagonist therapy. Additionally, they reviewed 28 additional cases identified in PubMed. The researchers found acute liver injury in all cases, most frequently autoimmunity and hepatocellular injury, but mixed non-autoimmune patterns and cholestasis (blocked flow of bile from the liver) also occurred. No deaths were attributed to the liver injury; one patient required a liver transplant, which was attributed to pre-existing cirrhosis with superimposed DILI.
Of the TNF-? antagonists, infliximab-associated liver injury has been the best documented, most likely because of its earlier approval and more wide-spread clinical use. Etanercept and adalimumab have also been linked to drug-induced liver injury. So far, there are no published cases found to be linked to natalizumab, golimumab or certolizumab.
The researchers found that liver damage was typically resolved following drug discontinuation, although some patients did benefit from a course of corticosteroids. Importantly, patients treated with an alternative TNF-? after resolution of their liver injury appeared to tolerate the drugs without recurrence.
"If patients who are taking these biologic agents experience symptoms such as abdominal pain, nausea and fatigue, physicians should check liver enzyme levels to determine if the symptoms are a result of these drugs," added Dr. Bonacini.
###
About the AGA Institute
The American Gastroenterological Association is the trusted voice of the GI community. Founded in 1897, the AGA has grown to include 17,000 members from around the globe who are involved in all aspects of the science, practice and advancement of gastroenterology. The AGA Institute administers the practice, research and educational programs of the organization. http://www.gastro.org.
About Clinical Gastroenterology and Hepatology
The mission of Clinical Gastroenterology and Hepatology is to provide readers with a broad spectrum of themes in clinical gastroenterology and hepatology. This monthly peer-reviewed journal includes original articles as well as scholarly reviews, with the goal that all articles published will be immediately relevant to the practice of gastroenterology and hepatology. For more information, visit http://www.cghjournal.org.
Like AGA (https://www.facebook.com/AmerGastroAssn) and Clinical Gastroenterology and Hepatology (http://www.facebook.com/cghjournal) on Facebook.
Join AGA on LinkedIn (http://www.linkedin.com/groups?mostPopular=&gid=915257).
Follow us on Twitter @AmerGastroAssn (http://www.twitter.com/amergastroassn).
Check out our videos on YouTube (http://www.youtube.com/amergastroassn).
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-04/aga-fub042913.php
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Apr. 29, 2013 ? Suppose you hear someone say, "The man gave the ice cream the child." Does that sentence seem plausible? Or do you assume it is missing a word? Such as: "The man gave the ice cream to the child."
A new study by MIT researchers indicates that when we process language, we often make these kinds of mental edits. Moreover, it suggests that we seem to use specific strategies for making sense of confusing information -- the "noise" interfering with the signal conveyed in language, as researchers think of it.
"Even at the sentence level of language, there is a potential loss of information over a noisy channel," says Edward Gibson, a professor in MIT's Department of Brain and Cognitive Sciences (BCS) and Department of Linguistics and Philosophy.
Gibson and two co-authors detail the strategies at work in a new paper, "Rational integration of noisy evidence and prior semantic expectations in sentence interpretation," published today in the Proceedings of the National Academy of Sciences.
"As people are perceiving language in everyday life, they're proofreading, or proof-hearing, what they're getting," says Leon Bergen, a PhD student in BCS and a co-author of the study. "What we're getting is quantitative evidence about how exactly people are doing this proofreading. It's a well-calibrated process."
Asymmetrical strategies
The paper is based on a series of experiments the researchers conducted, using the Amazon Mechanical Turk survey system, in which subjects were presented with a series of sentences -- some evidently sensible, and others less so -- and asked to judge what those sentences meant.
A key finding is that given a sentence with only one apparent problem, people are more likely to think something is amiss than when presented with a sentence where two edits may be needed. In the latter case, people seem to assume instead that the sentence is not more thoroughly flawed, but has an alternate meaning entirely.
"The more deletions and the more insertions you make, the less likely it will be you infer that they meant something else," Gibson says. When readers have to make one such change to a sentence, as in the ice cream example above, they think the original version was correct about 50 percent of the time. But when people have to make two changes, they think the sentence is correct even more often, about 97 percent of the time.
Thus the sentence, "Onto the cat jumped a table," which might seem to make no sense, can be made plausible with two changes -- one deletion and one insertion -- so that it reads, "The cat jumped onto a table." And yet, almost all the time, people will not infer that those changes are needed, and assume the literal, surreal meaning is the one intended.
This finding interacts with another one from the study, that there is a systematic asymmetry between insertions and deletions on the part of listeners.
"People are much more likely to infer an alternative meaning based on a possible deletion than on a possible insertion," Gibson says.
Suppose you hear or read a sentence that says, "The businessman benefitted the tax law." Most people, it seems, will assume that sentence has a word missing from it -- "from," in this case -- and fix the sentence so that it now reads, "The businessman benefitted from the tax law." But people will less often think sentences containing an extra word, such as "The tax law benefitted from the businessman," are incorrect, implausible as they may seem.
Another strategy people use, the researchers found, is that when presented with an increasing proportion of seemingly nonsensical sentences, they actually infer lower amounts of "noise" in the language. That means people adapt when processing language: If every sentence in a longer sequence seems silly, people are reluctant to think all the statements must be wrong, and hunt for a meaning in those sentences. By contrast, they perceive greater amounts of noise when only the occasional sentence seems obviously wrong, because the mistakes so clearly stand out.
"People seem to be taking into account statistical information about the input that they're receiving to figure out what kinds of mistakes are most likely in different environments," Bergen says.
Reverse-engineering the message
Other scholars say the work helps illuminate the strategies people may use when they interpret language.
"I'm excited about the paper," says Roger Levy, a professor of linguistics at the University of California at San Diego who has done his own studies in the area of noise and language.
According to Levy, the paper posits "an elegant set of principles" explaining how humans edit the language they receive. "People are trying to reverse-engineer what the message is, to make sense of what they've heard or read," Levy says.
"Our sentence-comprehension mechanism is always involved in error correction, and most of the time we don't even notice it," he adds. "Otherwise, we wouldn't be able to operate effectively in the world. We'd get messed up every time anybody makes a mistake."
The study was supported by a grant from the National Science Foundation.
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Story Source:
The above story is reprinted from materials provided by Massachusetts Institute of Technology. The original article was written by Peter Dizikes.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/living_well/~3/_IIiQYNk9ww/130429164950.htm
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KABUL, Afghanistan (AP) ? A remote-controlled roadside bomb killed three police officers in eastern Afghanistan on Sunday, an attack the Taliban claimed as the opening round of their spring offensive.
The bomb exploded in Ghazni province beneath a police convoy that was traveling to the district of Zana Khan to take part in a military operation against insurgents, Mohammad Ali Ahmadi, the province's deputy governor, told The Associated Press.
He said the blast destroyed the vehicle carrying Col. Mohammad Hussain, the deputy provincial police chief, killing him and two other officers. Ahmadi said two officers also were wounded in the insurgent operation, adding that it clearly targeted Hussain.
Taliban spokesman Zabiullah Mujahid claimed responsibility in an email sent to the media.
He called the bombing the first attack in the spring offensive that Taliban's leadership said it was starting Sunday. This year's offensive is named after Khalid ibn al-Walid, a companion of Islam's Prophet Muhammad who became a legendary Muslim military commander known as the "Drawn Sword of God." The insurgents said their forces planned to infiltrate enemy ranks to conduct so-called insider attacks and target military and diplomatic sites with suicide bombers.
Insurgents have escalated attacks recently in a bid to gain power and influence ahead of next year's presidential election and the planned withdrawal of most U.S. and other foreign combat troops by the end of 2014. U.S.-backed efforts to try to reconcile the Islamic militant movement with the Afghan government are gaining little traction.
April already has been the deadliest month this year for attacks across the country, where Afghan security forces are increasingly taking the lead on the battlefield in the war that has lasted more than 11 years.
On Saturday, a NATO plane crashed in southern Afghanistan, killing four international troops. The alliance said initial reports indicated no enemy activity in the area where the plane went down. Coalition personnel secured the site and were investigating the cause of the crash. NATO didn't identify the province where the crash occurred, but Mohammad Jan Rasoulyar, deputy governor of the southern province of Zabul, said an aircraft belonging to foreign forces crashed there on Saturday afternoon.
NATO declined on Sunday to provide any more information about the crash, including the type of aircraft involved, as the investigation continues.
Also on Sunday, the U.S.-led international military coalition said Afghan and foreign forces arrested six insurgents on Saturday ? three in Helmand province, one in Baghlan province and two in Kandahar province. The report said the two taken into custody in Kandahar city included a local Taliban leader who allegedly had coordinated assassinations, sniper ambushes and other attacks there against coalition and Afghan forces.
There are about 100,000 international troops in Afghanistan, including 66,000 Americans. A top priority of the U.S. force, which is slated to drop to about 32,000 by February 2014, is boosting the strength and confidence of Afghan forces.
___
Follow Thomas Wagner on Twitter at: www.twitter.com/tjpwagner
Source: http://news.yahoo.com/roadside-bomb-kills-3-policemen-afghanistan-051559967.html
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DUBAI (Reuters) - An Iranian scientist held for more than a year in California on charges of violating U.S. sanctions arrived in Iran on Saturday, Iranian media reported, after being freed in what the Omani foreign ministry said was a humanitarian gesture.
Mojtaba Atarodi, 55, an assistant professor of electrical engineering at Iran's Sharif University of Technology, had been detained on suspicion of buying high-tech U.S. laboratory equipment, previous Iranian media reports said.
The trade sanctions were imposed over Iran's nuclear program, which Iranian officials say is for peaceful energy purposes only but Washington says is secretly geared to developing the capability to produce nuclear weapons.
Iran's semi-official Mehr news agency said Atarodi arrived in Tehran on Saturday, after a stopover in Muscat on Friday.
Upon arriving at Tehran's Imam Khomeini airport on Saturday, Atarodi told reporters that he had tried to buy simple equipment for his personal lab to conduct academic research when he was detained by U.S. authorities, according to state-run Press TV.
There was no immediate U.S. comment on Atarodi's case.
Oman, a U.S.-allied Gulf Arab state which also enjoys good relations with Tehran, has previously helped mediate the release of Western prisoners held by the Islamic Republic.
Omani authorities had worked with U.S. officials to speed up Atarodi's case and return him home, the foreign ministry in Muscat said in a statement carried by local media.
He was released after follow-up approaches by Iran's foreign ministry, its spokesman Ramin Mehmanparast was quoted as saying by the Iranian Students' News Agency (ISNA).
In a report on its website dated January 7, 2012, Press TV said Atarodi was taken into custody on his arrival in Los Angeles on December 7, 2011, accused of buying advanced lab equipment.
Iran and the United States severed relations after the 1979 Islamic Revolution that overthrew the pro-Western monarchy in Tehran.
In 2011, Iran freed into Omani custody two U.S. citizens who had been sentenced to eight years in jail for spying.
Josh Fattal and Shane Bauer, among three people arrested while hiking along the Iraq-Iran border in 2009, were flown to Oman after officials there helped secure their release by posting bail of $1 million. They denied being spies.
The third detainee, Sarah Shourd, had been freed in September 2010, also by way of Oman.
(Reporting by Saleh al-Shaybani and Sami Aboudi; additional reporting by Zahra Hosseinian in Zurich and Yeganeh Torbati in Dubai; Editing by Mark Heinrich)
Source: http://news.yahoo.com/iranian-scientist-freed-u-returns-home-local-media-115447735.html
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COPENHAGEN, Denmark (AP) ? A fire blazed through The Museum of Danish Resistance in Copenhagen on Sunday, destroying large parts of the building but most of the collection was saved, museum officials said.
No one was injured in the fire and firefighters and staff who rushed to the scene in central Copenhagen managed to save the majority of display items, museum spokesman Henrik Schilling said.
The fire started in the museum cafe around 2 a.m. and quickly spread to the exhibition hall. The last pockets of fire were being extinguished shortly after noon, Schilling said.
The museum is an affiliate of the Danish National Museum and exhibits objects related to the Danish resistance to the German occupation during World War II. The wooden building, located close to the waterfront, was built specifically for its purpose in the 1950s, Schilling said.
Nazi Germany's occupation of Denmark started on April 9, 1940, and continued until the Germans surrendered to the Allies on May 5, 1945. The Danish resistance movement distributed illegal flyers and upheld secret radio communication with the British. The resistance grew stronger toward the end of the war, when acts of violent sabotage against factories and railways increased.
The cause of the fire is not yet known. Schilling said it is still unclear if the building can be restored or needs to be rebuilt entirely.
Source: http://news.yahoo.com/fire-destroys-danish-museum-collection-saved-112137703.html
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HTC has posted the 1.29.1540.3 factory restore images for the unlocked Developer Edition HTC One on the HTCdev site. Available in two flavors -- a zip file and a Windows RUU executable -- these files will allow anyone to restore their phone back to an out-of-the-box condition as long as there is access to the bootloader. That means no matter how bad you've screwed the system firmware up from monkeying around with it, you have an easy path back to stock settings. Then you can do it all over again.
Posting two different versions is pretty nice, too. The Windows only RUU is simple to use for folks running Windows (just plug in the phone and run the program), but not everyone uses Windows. For those folks who use a Mac or Linux computer, the zip file and fastboot makes it easy to go back without building a VM with Windows to do so.
Be aware that these images are only for the unlocked Developer Edition, so don't try to just flash them to your carrier model. Your favorite ROM developer will have something for you instead. It's recommended that everyone with one of the Developer Edition models have these files in a safe place "just in case", so grab the 980MB file at the link below.
Source: HTCdev
| |
Source: http://feedproxy.google.com/~r/androidcentral/~3/9lLwwpqCFSg/story01.htm
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Apr. 26, 2013 ? New research shows that movement of the ring-like molecule pyrrole over a metal surface runs counter to the centuries-old laws of 'classical' physics that govern our everyday world.
Using uniquely sensitive experimental techniques, scientists have found that laws of quantum physics -- believed primarily to influence at only sub-atomic levels -- can actually impact on a molecular level.
Researchers at Cambridge's Chemistry Department and Cavendish Laboratory say they have evidence that, in the case of pyrrole, quantum laws affecting the internal motions of the molecule change the "very nature of the energy landscape" -- making this 'quantum motion' essential to understanding the distribution of the whole molecule.
The study, a collaboration between scientists from Cambridge and Rutgers universities, appeared in the German chemistry journal Angewandte Chemie earlier this month.
A pyrrole molecule's centre consists of a "flat pentagram" of five atoms, four carbon and one nitrogen. Each of these atoms has an additional hydrogen atom attached, sticking out like spokes.
Following experiments performed by Barbara Lechner at the Cavendish Laboratory to determine the energy required for movement of pyrrole across a copper surface, the team discovered a discrepancy that led them down a 'quantum' road to an unusual discovery.
In previous work on simpler molecules, the scientists were able to accurately calculate the 'activation barrier' -- the energy required to loosen a molecule's bond to a surface, allowing movement -- using 'density functional theory', a method that treats the electrons which bind the atoms according to quantum mechanics but, crucially, deals with atomic nuclei using a 'classical' physics approach.
Surprisingly, with pyrrole the predicted 'activation barriers' were way out, with calculations "less than a third of the measured value." After much head scratching, puzzled scientists turned to a purely quantum phenomenon called 'zero-point energy'.
In classical physics, an object losing energy can continue to do so until it can be thought of as sitting perfectly still. In the quantum world, this is never the case: everything always retains some form of residual -- even undetectable -- energy, known as 'zero-point energy'.
While 'zero-point energy' is well known to be associated with motion of the atoms contained in molecules, it was previously believed that such tiny amounts of energy simply don't affect the molecule as a whole to any measurable extent, unless the molecule broke apart.
But now, the researchers have discovered that the "quantum nature" of the molecule's internal motion actually does affect the molecule as a whole as it moves across the surface, defying the 'classical' laws that it's simply too big to feel quantum effects.
'Zero-point energy' moving within a pyrrole molecule is unexpectedly sensitive to the exact site occupied by the molecule on the surface. In moving from one site to another, the 'activation energy' must include a sizeable contribution due to the change in the quantum 'zero-point energy'.
Scientists believe the effect is particularly noticeable in the case of pyrrole because the 'activation energy' needed for diffusion is particularly small, but that many other similar molecules ought to show the same kind of behavior.
"Understanding the nature of molecular diffusion on metal surfaces is of great current interest, due to efforts to manufacture two-dimensional networks of ring-like molecules for use in optical, electronic or spintronic devices," said Dr Stephen Jenkins, who heads up the Surface Science Group in Cambridge's Department of Chemistry.
"The balance between the activation energy and the energy barrier that sticks the molecules to the surface is critical in determining which networks are able to form under different conditions."
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What are adaptive sports and recreation programs??
Adaptive and accessible sports and recreation programs are recreational activities that are modified or designed to allow people with disabilities to participate. Almost any type of recreational activity can be adapted or made accessible for people with physical, visual, cognitive, or emotional disabilities.Adaptive and accessible sports and recreation programs include a wide range of activities:
Some programs are disability-specific. Disability-specific programs may limit participation to people with certain types of impairments.
You should check with the programs that interest you to see if they have any restrictions.
How much does it cost?
Many adaptive and accessible sports and recreation programs are free, but some charge fees. Financial aid, scholarships, or sliding fee scales are usually available for families and individuals who need assistance.
You should check with the programs that interest you to see if they charge fees. If they do, ask about financial assistance if you need help paying.
What programs are offered in the state parks and recreation areas?
The Massachusetts Department of Conservation and Recreation (DCR) oversees the state's Universal Access Program. The Universal Access Program provides adaptive and/or accessible outdoor recreation programs for people of all abilities in state parks and recreation areas throughout Massachusetts.
Web site: Department of Conservation and Recreation's Universal Access Program
Parks and programs: Universal Access Brochure
Newsletter: Universal Access Program Newsletter, Registration Form, and Schedule
Schedule of events: Accessible Events
For information about specific activities, visit the following DCR web site pages:
Where can I find adaptive sports and recreation programs?
The Massachusetts Universal Access Program offers a wide range of activities in state parks and recreation areas.
Other adaptive sports and accessible recreation programs in Massachusetts include:
(Note: For additional programs, see Directories below)
AccesSportAmerica
AccesSportAmerica, a national nonprofit organization based in Massachusetts, offers high-challenge sports and training programs for children and adults of all disabilities. Programs are offered year-round in the Greater Boston area. High-challenge sports include adaptive windsurfing, outrigger canoeing, surfing, water skiing, sailing, rowing, wall climbing, tennis, soccer, and cycling.
All Out Adventures
All Out Adventures is a nonprofit organization that provides year-round outdoor activities for people with disabilities and their friends and family. Programs are inclusive, allowing children and adults of all abilities to participate together. All Out Adventures runs programs for the state Universal Access Program and the Statewide Head Injury Program.
CHD Disability Resources Adaptive Sports and Activities
CHD Disability Resources' barrier-free sports and recreation programs are open to anyone with physical disabilities or visual impairments in the Springfield MA area. Adult and junior sports programs include sled hockey, swimming, cycling, golf, wheelchair basketball, soccer, and more. Adaptive sports equipment is available for borrowing for personal use.
Kids in Disability Sports (K.I.D.S.)
K.I.D.S. is a volunteer-run non-profit organization based in Lowell MA that provides a wide range of sports and recreation activities for children and young adults with special needs. K.I.D.S. specialized athletic programs serve families throughout the Merrimack Valley, and include team sports such as basketball, baseball, and soccer; as well as swimming, horseback riding, martial arts, golf, bowling, and many other activities.
Little League Baseball ? Challenger Division - Massachusetts
The Challenger Division is a special division of Little League baseball for boys and girls with physical and intellectual disabilities, ages 5 through 18 (or completion of high school). Players are placed on teams according to ability, not age, and volunteer ?buddies? help out as needed.n
Paralympics USA and Paralympic Sport Clubs
U.S. Paralympics is the division of the U.S. Olympic Committee for athletes with physical and visual disabilities. The U.S. Paralympic Team participates in the Paralympics, a competition for elite paralympic sport athletes, held at the same time and place as the Olympics.
Paralympic Sport Clubs are community-based programs where youth and adults with physical and visual disabilities can take part in paralympic sports regardless of skill level.
Special Olympics ? Massachusetts (SOMA)
The Massachusetts Special Olympics offers a wide range of Olympic-style individual and team sports and training for children and adults with intellectual disabilities. Activities are year-round, and include Winter Games, Summer Games, special tournaments, and training. The cost is free.
Sudbury Inclusive and Adaptive Sports and Recreation Program?
TOPSoccer - Massachusetts Youth Soccer?
Ultimate Sports Program
The Ultimate Sports Program (USP) - "Social Inclusion Through Sports" - teaches sports to children with disabilities alongside their friends. The USP runs programs in various Western Massachusetts locations. All programs are free, and include swimming, basketball, sled hockey, baseball, Taekwondo, wiffleball, bowling, rock climbing, and more.
Sports and Recreation Directories
?DisabilityInfo.org
Playgrounds: Accessible and Inclusive Playgrounds
Boundless Playgrounds?
Accessible Playgrounds - Massachusetts
Accessible and inclusive playgrounds are barrier-free playgrounds where children and adults of all abilities can play together.
National Center on Physical Activity and Disability (NCPAD) - Massachusetts
Accessible Programs in Massachusetts
Programs are listed by town, or by keyword search. The NCPAD directory includes fitness programs, competitive and leisure sports, and other physical activities, with an emphasis on health benefits of physical activity.
Spinal Cord Injury Association - Greater Boston Chapter
Directory: Recreation and Sports for People with Disabilities
This directory of adaptive programs for youth and adults with spinal cord injuries includes outdoor activities, high-challenge sports, wheelchair basketball, quad rugby, and many other sports and physical activities.
Sports and Gyms, Winter and Summer Activities - Special Needs Resources for Massachusetts
?Sports and Gyms Posts - Summer Programming ? &? Winter Programming
Special Needs Resources for Massachusetts is an online resource for families of children with special needs, with a focus on autism resources in eastern Massachusetts. The Sports and Gyms, Summer Programming, and Winter Programming posts include a variety of current and seasonal sports and recreation programs.
Therapeutic Horsemanship: PATH centers
Directory: PATH: Find a Center
PATH Therapeutic Horsemanship centers offer equine assisted activities and therapies to help children and adults with a range of physical, cognitive, and emotional challenges. Activities include horseback riding, vaulting, and carriage driving. Financial assistance may be available.
Local YMCAs and ARC Chapters also offer adaptive and accessible recreation and sports programs for their members and the community.
?
What are the laws regarding adaptive and accessible sports and recreation?
The federal Americans with Disabilities Act (ADA) prohibits discrimination on the basis of disability. In Recreation Access Rights Under the ADA, the National Center on Accessibility outlines some of the rights created by the ADA with respect to sports and recreation:
The ADA rules apply to government facilities and programs, nonprofit organizations (such as YMCAs), and private organizations (such as health clubs and gyms). The only exempt organizations are private membership clubs and religious organizations.
__________________________________________________________________________________________________
Automotive Innovations?
1000 Main St? Bridgewater, MA??
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Source: http://newenglandmobilitydealer.blogspot.com/2013/04/adaptive-sports-and-accessible.html
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Tired of how much your PlayStation 3 doesn't look like a Terminator robot? Us too, especially given that hilariously mechanical new top-loading disc drive cover. Thankfully, Sony sympathizes with our plight, announcing this week that its "Metallic Gray" DualShock 3 controller for the PlayStation 3 will arrive in the United States in a few months (it's been available in Japan for some time). On June 3rd, the controller becomes available for the standard DS3 price of $54.99, and interested parties can pre-order right this second if they so choose. Of course, we don't anticipate a shortage when they arrive this June, but it's always possible that a T-800 will be sent back from the future to accessorize. In which case, you pre-order folks end up looking pretty good.
Filed under: Gaming, Handhelds, Peripherals, Sony
Via: Joystiq
Source: Sony
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Public release date: 26-Apr-2013 Share ] Contact: Megan Beech
m.beech@hud.ac.uk
01-484-473-053
University of Huddersfield
Dr Jason Roach of the University of Huddersfield, along with co-author Professor Ken Pease, has published a new book addressing the controversial issue of employing evolutionary theory to analyse criminal behaviour. UK criminologists have so far shied away from this approach for fear of being linked to less credible theories such as eugenics. Dr Roach, writing alongside one of the world's most respected criminologists, hopes to readdress this balance and encourage new researchers to consider the insights evolutionary theory has to offer.
Child homicide is one example of a crime which can often be comprehended more easily if evolution is introduced into the analysis, according to Dr Roach. He explains that such crimes might be better understood when considering that an evolutionary instinct could mean that some men feel little need to invest any parental responsibility in children who are not biologically theirs as in the tragic case of baby Peter Connolly.
An understanding of the evolutionary process who we are as a species and where we have evolved from can also explain how and why legal systems have developed, as a means of regulating competition between individuals. Dr Roach has also explored empathy and altruism unique to human beings and how they function as protective factors to mitigate anti-social behaviour.
"The default position is one of empathy, so those that do engage in anti-social behaviour should perhaps be nudged towards being more empathic, rather than just simply punished," argues Dr Roach, who is Reader in Crime and Policing at the University of Huddersfield.
His new book, co-authored with Professor Pease, is entitled Evolution and Crime. It argues that although the received scientific wisdom is that human physique and behaviour have been shaped by the pressures of natural selection, the topic of crime is rarely touched on in textbooks on evolution and the topic of evolution is ever rarer in criminology textbooks.
There could be practical applications to his work on evolution and crime, he added. For example, most crime was committed by males aged 16-24, more likely to take risks because they feel they have nothing to lose.
"If you look at our society it is older men that wield all the power. Rich older men also attract young females, which you might say gives them a distinct advantage over their younger counterparts," said Dr Roach.
"Most young men who commit crime eventually desist by their late twenties, mainly because they 'grow up'. So we need to speed that process up and give them a sense of hope that their time will come and stop them taking all these risks."
###
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 26-Apr-2013 Share ] Contact: Megan Beech
m.beech@hud.ac.uk
01-484-473-053
University of Huddersfield
Dr Jason Roach of the University of Huddersfield, along with co-author Professor Ken Pease, has published a new book addressing the controversial issue of employing evolutionary theory to analyse criminal behaviour. UK criminologists have so far shied away from this approach for fear of being linked to less credible theories such as eugenics. Dr Roach, writing alongside one of the world's most respected criminologists, hopes to readdress this balance and encourage new researchers to consider the insights evolutionary theory has to offer.
Child homicide is one example of a crime which can often be comprehended more easily if evolution is introduced into the analysis, according to Dr Roach. He explains that such crimes might be better understood when considering that an evolutionary instinct could mean that some men feel little need to invest any parental responsibility in children who are not biologically theirs as in the tragic case of baby Peter Connolly.
An understanding of the evolutionary process who we are as a species and where we have evolved from can also explain how and why legal systems have developed, as a means of regulating competition between individuals. Dr Roach has also explored empathy and altruism unique to human beings and how they function as protective factors to mitigate anti-social behaviour.
"The default position is one of empathy, so those that do engage in anti-social behaviour should perhaps be nudged towards being more empathic, rather than just simply punished," argues Dr Roach, who is Reader in Crime and Policing at the University of Huddersfield.
His new book, co-authored with Professor Pease, is entitled Evolution and Crime. It argues that although the received scientific wisdom is that human physique and behaviour have been shaped by the pressures of natural selection, the topic of crime is rarely touched on in textbooks on evolution and the topic of evolution is ever rarer in criminology textbooks.
There could be practical applications to his work on evolution and crime, he added. For example, most crime was committed by males aged 16-24, more likely to take risks because they feel they have nothing to lose.
"If you look at our society it is older men that wield all the power. Rich older men also attract young females, which you might say gives them a distinct advantage over their younger counterparts," said Dr Roach.
"Most young men who commit crime eventually desist by their late twenties, mainly because they 'grow up'. So we need to speed that process up and give them a sense of hope that their time will come and stop them taking all these risks."
###
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-04/uoh-hrp042613.php
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Lauren Schreiber, 26, converted to Islam in 2010 after a study-abroad trip. She and others want to dispel stereotypes that have sprung up after news reports about Katherine Russell, 24, the U.S.-born wife of suspected Boston bomber Tamerlan Tsarnaev.
By JoNel Aleccia, Senior Writer, NBC News
When an American convert to Islam was revealed as the wife of the dead Boston bombing suspect, Lauren Schreiber wasn?t surprised at what came next.
Comments from former acquaintances and complete strangers immediately suggested that 24-year-old Katherine Russell, a New England doctor?s daughter, must have been coerced and controlled by her husband, Tamerlan Tsarnaev, who died last week in a firefight with police.
?She was a very sweet woman, but I think kind of brainwashed by him,? reported the Associated Press, quoting Anne Kilzer, a Belmont, Mass., woman who said she knew Russell and her 3-year-old daughter.
That kind of assumption isn?t new to Schreiber, 26, a Greenbelt, Md., woman who became a Muslim in 2010.
?The moment you put on a hijab, people assume that you?ve forfeited your free will,? says Schreiber, who favors traditional Islamic dress. ?
The Boston terror attack and the questions about whether Russell knew about her husband?s deadly plans have renewed stereotypes and misconceptions that U.S. women who have chosen that faith say they want to dispel.
?It?s not because somebody made me do this,? explains Schreiber, who converted after a college study-abroad trip to West Africa. ?It?s what I choose to do and I?m happy.?
Rebecca Minor
Rebecca Minor, 28, of West Hartford, Conn., converted to Islam five years ago. Wearing a hijab "reminds me to be a good person," she said.
Her view is echoed by Rebecca Minor, 28, of West Hartford, Conn., a special education teacher who converted to Islam five years ago. When her students, ages 5 to 8, ask why she wears a headscarf, she always says the same thing:?"It's something that's important to me and it reminds me to be a good person," says Minor, who is secretary for the Muslim Coalition of Connecticut.?
Muslims make up less than 1 percent of the U.S. population, according to studies by the Pew Forum on Religion and Public Life. In 2011, about 1.8 million U.S. adults were Muslim, and about 20 percent had converted to the faith, Pew researchers say. Of those converts, about 54 percent were men and 46 percent were women. About 1 in 5 converts mentioned family factors, including marrying a Muslim, as a reason for adopting the faith.?
Accusations are 'harsh'
Women convert for a wide range of reasons -- spiritual, intellectual and romantic -- says Yvonne Haddad, a professor of the history of Islam and Christian-Muslim relations at Georgetown University.
?Islam is attractive to women that the feminist movement left behind,? says Haddad, who co-authored a 2006 book, ?Muslim Women in America: The Challenge of Islamic Identity Today.?
Women like Lindsey Faraj, 26, of Charlotte, N.C., say that wearing a headscarf and other traditional Islamic garb in public often leads people to assume she sacrificed her American life to please a man.
?'You must have converted in order to marry him,' I hear it all the time,? says Faraj, who actually converted simultaneously with her husband, Wathek Faraj, who is from Damascus, about four years ago.?
She?s also heard people say that her husband is allowed to beat her, that she?s not free to get a divorce, that she and her two children, ages 4 months and 2, are subservient to the man. Such concepts are untrue, of course, she says.
Lindsey Faraj, 26, of Charlotte, N.C., converted to Islam four years ago. She says it was thoughtful, heart-felt choice that changed her life.
?In the beginning, it did offend me a lot,? says Faraj, who grew up in a Christian family in Florida. ?But now as my sense of my new self has grown, I don?t feel offended.?
She?s able to joke, for instance, about the woman who screamed insults from a passing car.
?They screamed: ?Go back to your own country? and I thought, ?It doesn?t get more white than this, girl,?? says Faraj, indicating her fair features.?
Like all stereotypes, such views are steeped in fear, says Haddad.
?Accusations of brainwashing are harsh,? she says. ?They cover up the fact that we don?t comprehend why people like ?us? want to change and be like ?them.??
All three women say they came to Islam after much thought and spiritual searching.
Islam 'entered my heart'
Schreiber, who is a community outreach and events coordinator for the Council on American-Islamic Relations, says she was drawn to the religion after meeting other Muslims on her trip abroad before graduating from St. Mary's College of Maryland in 2009.?
She grew up in an agnostic family where she was encouraged to discover her own faith.?
"It was, whatever you decide to do -- temple, church, mosque -- I support you finding yourself," says Schreiber. She's now married to a Muslim man, Muhammad Oda, 27, whose parents were both converts to Islam. She said came to the faith before the relationship.??
Faraj, a stay-at-home mom, says she never saw herself "as a religious person, in the least," but became enthralled after trying to learn more about Islam before a visit to see her husband's family.?
?The concept of Islam hit me,? Faraj recalls. ?It was just something that entered my heart.?
Minor, who is single, says she was intrigued by Islam in college, when she was?close friends with?a deployed?American Marine but had Muslim friends at school.
"I saw a huge discrepancy in the negative things I heard coming from my?(friend)?and the actions I could see in my co-workers," she recalls. After spending 18 months learning about Islam, she decided to convert.?
The response from family and friends has been overwhelmingly supportive, Minor says.?
"The more you can do to educate people about Islam, not by preaching, but by actions, the better," she says.?
Reports that Katherine Russell might have been embroiled in an abusive relationship, or that her husband intimidated her aren?t an indictment of Islam, Haddad says.?
"Abusive men come in all colors, nationalities, ethnicities and from all religions," she says. "No one says that Christianity teaches abuse of women because some Christian men are abusive."
Schreiber says she frequently gets comments from people surprised to see her fair skin and hear her American accent from beneath a scarf. She says she appreciates it when people actually ask questions instead of making assumptions.
?I just want people to know that there are American Muslim women who wear hijab by choice because they believe in it and it feels right to them, not because anyone tells them to.?
Related stories:?
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(Reuters) - Biopharmaceutical company Theravance Inc said it plans to split into two publicly traded companies, one of which would independently manage the development of the respiratory drugs it is working on with GlaxoSmithKline Plc.
The split plan comes after weeks of speculation that the company could be bought by Glaxo, Theravance's largest shareholder with a stake of about 27 percent.
Theravance shares were up about 10 percent at $33.50 in after-hours trading on Thursday.
The other company to result from the split will focus on development of small-molecule compounds in rare disease areas.
Theravance Chief Executive Rick Winningham said the split would unlock potential value from two disparate sets of assets, better align employee incentives and provide a consistent return of capital to stockholders of the Glaxo partner, to be called Royalty Management Co.
The second company will be called Theravance Biopharma.
Theravance's shares rose sharply in early March after Piper Jaffray said in a research report that Glaxo could take over Theravance if U.S. health regulators ruled positively on the companies' respiratory drugs, Breo Ellipta and Anoro.
An advisory panel to the U.S. Food and Drug Administration recommended earlier this month that the agency approve Breo Ellipta to treat smoking-related lung damage.
Theravance's shares have risen more than 10 percent since then up to Thursday close of $30.92. The stock was trading at $33.50 after hours.
Theravance also reported a first-quarter net loss of $37.4 million, or 39 cents per share, compared with a profit of $84.6 million, or $1.01 per share, a year earlier.
Revenue fell by $125.8 million to $1.3 million. The steep fall in revenue reflected the scrapping in January of Theravance's global deal with Japan's Astellas Pharma Inc to develop and market its antibiotic Vibativ.
Analysts on average had expected a loss of 38 cents per share on revenue of $2.3 million, according to Thomson Reuters I/B/E/S.
(Reporting by Zeba Siddiqui in Bangalore; Editing by Don Sebastian, Maju Samuel)
Source: http://news.yahoo.com/theravance-split-two-listed-companies-215253650--finance.html
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WASHINGTON (AP) ? With flight delays mounting, the Senate has passed legislation to end air traffic controller furloughs blamed for inconveniencing large numbers of travelers.
Approval came without dissent, and long after many senators had left the Capitol for a weeklong vacation.
A House vote is expected as early as Friday.
Under the measure, the Federal Aviation Administration would gain authority to transfer up to $253 million from accounts that are flush into other programs, to "prevent reduced operations and staffing" through the Sept. 30 end of the fiscal year.
Officials said that would likely be enough to restore full staffing for the furloughed controllers, as well as prevent the closure of small airport towers.
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HBO via YouTube
Hey, Ned Stark! "I'll be there for youuuuuuu ..." Except, well, that one time when you really needed me.
By Kurt Schlosser, TODAY
It's tough to remember the last time we heard the "Friends" theme song and thought about chopping someone's head off. But a fresh take on the "Game of Thrones" viral video set to "I'll Be There For You" has rekindled the fun and troubling juxtaposition.
Is there really that much smiling and laughter in the HBO fantasy series that we watch because it's full of swordplay, sex and dragons? With that clappy music playing over the top of "Thrones" clips, we'll believe anything!
Tyrion Lannister slaps Joffrey Baratheon! "So no one told you life was gonna be this wayyyyyy ... clap clap clap clap clap."
Jamie Lannister pushes little Bran Stark out of the tower! Paralyzing hysterics!
Ned Stark loses his head? Cut to giggling Cersei Baratheon! (Wait -- that actually feels natural.)
The video by YouTube user YuesWoman follows at least one other attempt at mixing "Thrones" and "Friends." And we've seen how our other favorite dark shows -- "Breaking Bad" and "The Walking Dead" -- have seen the light of the '90s with reimagined theme music.
But the next time we tune in to "Thrones" to see someone take an arrow in the chest, we can't help but worry Rachel or Chandler or Phoebe will be in our heads laughing or hugging it out. "Clap clap clap clap clap!"
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WASHINGTON (AP) ? The richest Americans got richer during the first two years of the economic recovery while average net worth declined for the other 93 percent of U.S. households, says a report released Tuesday.
The upper 7 percent of households owned 63 percent of the nation's total household wealth in 2011, up from 56 percent in 2009, said the report from the Pew Research Center, which analyzed new Census Bureau data released last month.
The main reason for the widening wealth gap is that affluent households typically own stocks and other financial holdings that increased in value, while the less wealthy tend to have more of their assets in their homes, which haven't rebounded from the plunge in home values, the report said.
Tuesday's report is the latest to point up financial inequality that has been growing among Americans for decades, a development that helped fuel the Occupy Wall Street protests.
A September Census Bureau report on income found that the highest-earning 20 percent of households earned more than half of all income the previous year, the biggest share in records kept since 1967. A 2011 Congressional Budget Office report said incomes for the richest 1 percent soared 275 percent between 1979 and 2007 while increasing just under 40 percent for the middle 60 percent of Americans.
Other details of Tuesday's new report:
?Overall, the wealth of American households rose by $5 trillion, or 14 percent, during the period to $40.2 trillion in 2011 from $35.2 trillion in 2009. Household wealth is the sum of all assets such as a home, car and stocks, minus the sum of all debts.
?The average net worth of households in the upper 7 percent of the wealth distribution rose by an estimated 28 percent, while that of households in the lower 93 percent dropped by 4 percent. That is, the mean wealth of the 8 million households in the more affluent group rose to an estimated $3.2 million from an estimated $2.5 million while that of the 111 million households in the less affluent group fell to roughly $134,000 from $140,000.
?The upper 7 percent were the households with a net worth above $836,033 and the 93 percent represented households whose worth was at or below that. Not all households among the 93 percent saw a decline in net worth, but the average amount declined for that group.
?On an individual household basis, the average wealth of households in the more affluent group was almost 24 times that of those in the less affluent group in 2011. At the start of the recovery in 2009, that ratio was less than 18 to 1.
?During the study period, Standard & Poor's 500 stock index rose by 34 percent, while the Standard & Poor's/Case-Shiller index for home prices fell by 5 percent.
___
Online:
Pew Research Center: www.pewresearch.org
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